Sparks and Frictions is the title of the third edition of Re:Humanism Art Prize, which since 2018 is dedicated to exploring the relationship between art and artificial intelligence. This edition consolidates the idea of contemporary art as an agent capable of arousing reflections and developing imaginations about the future to come but also to oppose technocratic regimes as part of sustainable and inclusive development. With this edition, the program expands through the relationship with all forms of technological media and scientific topics that bring important reflections on identity, relationships and possible futures into play. From quantum technologies to metaverse, from genetics and biohacking, while retaining a look at the new scenarios of AI, will be evaluated different forms of artistic speculation that, as in each edition, should not necessarily involve the direct use of the technologies concerned.